Currently active BPN Biologics projects listed on this page have received grant funding, along with expert consultants and CRO (contract research organization) contracts sponsored by NIH. Click on a project to receive more information (abstracts, publications, patents, contacts) via the NIH RePORTER database.
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| Title | Disorder | Modality | PI/Lead Investigator | Institution |
|---|---|---|---|---|
| Development of anti-LTBP4 as a biologic to treat Neuromuscular Diseases | Duchenne Muscular Dystrophy | Monoclonal antibody | Alexis Demonbreun | Northwestern University at Chicago |
| Preclinical and Early Clinical Development of a Novel Drug for On-Demand Voiding | Spinal cord injury | Peptide | Edward Burgard | Dignify Therapeutics, LLC |
| Development of Utrophin Site Blocking Oligos (SBOs) to treat Duchenne Muscular Dystrophy (DMD) | Duchenne Muscular Dystrophy | Site blocking oligonuclotide | Tejvir S. Khurana | University of Pennsylvania |
| Development of AAV-AIBP for neuroprotecction in glaucoma | Glaucoma | AAV-encoding protein | Wonkyu Ju | University of California- San Diego |
| Procession to IND of a capsid mutated AAV8 codon optimized NAGLU vector for treatment of Sanfilippo Syndrome type B | Sanfilippo Syndrome | Gene Therapy | Coy Heldermon | University of Florida |