Blueprint Research Initiatives

rainbow colored brain image

The NIH Blueprint for Neuroscience Research supports cross-cutting neuroscience activities like research training, workforce diversity, informatics, therapeutic development, and research initiatives. Blueprint will be announcing exciting new research initiatives now and throughout 2021.

Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program
The first announcement is part of the NIH’s Faculty Institutional Recruitment for Sustainable Transformation (FIRST) program. All NIH Blueprint Institutes and Centers participate in NIH Common Fund initiatives. The FIRST program will provide support to institutions to recruit diverse groups or “cohorts” of early-stage neuroscience research faculty and prepare them to thrive as NIH-funded researchers. Progress has been made to increase participation of historically underrepresented groups in biomedical research training stages, however members of these groups are still less likely to be hired into positions as independently-funded faculty researchers, according to previous studies. These groups include underrepresented racial and ethnic groups, individuals with disabilities, individuals from disadvantaged backgrounds, and women. Two new funding announcements have been released as part of the NIH Common Fund’s FIRST program to enhance inclusive excellence at NIH-funded institutions.
Inclusive excellence has diversity and equity at its core, building inclusion into all organizational functions and establishing hallmarks for successful operationalization of inclusion. The FIRST program will provide funds for faculty recruitment and to establish inclusive environments at participating institutions to help those faculty succeed. The program’s estimated budget is $241 million over nine years, pending the availability of funds.

Tools and Technologies to Explore Nervous System Biomolecular Condensates
The purpose of this funding opportunity announcement (FOA) is to support the development of innovative tools and/or technologies to monitor or manipulate biomolecular condensates (BMCs) in vivo and enable investigators to adopt these tools to answer outstanding questions in basic neuroscience. This research will transform our understanding of the mechanistic role of BMCs in human nervous system health and disease and may serve as the foundation for the development of novel BMC-based therapeutics.

Please visit the Funding Opportunities webpage for a searchable list of all Blueprint FOAs and notices.

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Form Approved OMB# 0925-0648 Exp. Date 05/31/2021