Notice of Funding Opportunity (NOFO) Title: RFA-AA-18-07: NIH Blueprint for Neuroscience Research: Dynamic Neuroimmune Interactions in the Transition from Normal CNS Function to Disorders (R01)
The goal of this NOFO is to transform our understanding of how dynamic interactions among multiple cell types involved in neuroimmune interactions (e.g., neurons, glia cells, neurovascular units, or other neuroimmune components) mediate the transition from normal central nervous system (CNS) function to disorder conditions. The NOFO encourages projects combining diverse expertise and innovative approaches to address these questions at the molecular, cellular, and circuitry levels. Eight funded projects investigate the onset and progression of neurodegenerative diseases, neuropathic pain, alcohol-related disorders, and neurodevelopmental disorders. The outcomes of these studies provide an integrated view of the dynamics of multiple neuroimmune components and their contributions to the onset and progression of CNS disorders.
Program Lead: Changhai Cui, PhD
Below is a list of projects funded under RFA-AA-18-07.
Funded Projects
Project Title: Relating neuroimmune and neurovascular alterations during Alzheimers Disease progression
Awardee: YASEEN, MOHAMMAD ABBAS
Project Information: 1R01AA027097-01
Project Title: The neuroimmune model of excessive alcohol consumption: Transition to Alcohol Use Disorder
Awardee: PONOMAREV, IGOR
Project Information: 1R01AA027096-01
Project Title: The role of neuroimmune interactions in the pathogenesis of chronic pain
Awardee: YANG, GUANG
Project Information: 1R01AA027108-01
Project Title: Dynamic neuroimmune interactions in the onset and progression of FASD
Awardee: KANE, CYNTHIA J/DREW, PAUL D (contact); MAJEWSKA, ANNA K
Project Information: 1R01AA027111-01
Project Title: MECHANISMS OF TRPV4-MEDIATED NEUROPATHIC PAIN
Awardee: HU, HONGZHEN
Project Information: 1R01AA027065-01
Project Title: Mechanisms of synaptic loss by the classical complement pathway in motor circuit development and disease
Awardee: MENTIS, GEORGE ZACHARIAS
Project Information: 1R01AA027079-01
Project Title: Neuroimmune interactions in Rett syndrome
Awardee: LASALLE, JANINE M
Project Information: 1R01AA027075-01
Project Title: Single Cell Analyses of Neuroimmune Dysfunctions in the Thalamocortical Circuit in FTLD
Awardee: HUANG, ERIC J (contact); KRIEGSTEIN, ARNOLD
Project Information: 1R01AA027074-01