Current Drug Development Projects

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Title Disorder PI Investor Contacts Institution
Developing Non-Muscle Myosin II Inhibitors for Substance Use Relapse Stimulant use disorder Miller, Courtney Miller, Courtney Scripps Florida
Development of an Oral Analgesic for Neuropathic Pain Neuropathic Pain Buckpitt, Alan Buckpitt, Alan EicOsis, LLC
Development of Human 12/15-lioxygenase therapeutics for stroke Stroke van Leyen, Klaus van Leyen, Klaus Massachusetts General Hospital
Discovery of NaV1.7 Inhibitors for the Treatment of Pain Pain Mulcahy, John Vincent Mulcahy, John Vincent Siteone Therapeutics, Inc.
Discovery of non-addictive KOR antagonists for migraine prophylaxis Migraine van Orden, Lori Jean Blackthorn Therapeutics
Discovery/Development of GABA-A Α5 Positive Allosteric Modulators for Treatment of MCI Due to AD Alzheimer's Disease Rozenzweig-Lipson, Sharon Rozenzweig-Lipson, Sharon AgeneBio, INC.
EP2 Antagonist Development for Post-seizure Cognitive Deficits Cognitive deficits/Epilepsy Dingledine, Raymond Dingledine, Raymond Emory University
Inhibitors of TrkB Signaling Temporal Lobe Epilepsy McNamara, James McNamara, James Duke University
Kv7.2/7.3 Activators for the Treatment of Epilepsy Disorders Epilepsy Disorders Bozik, Michael Bozik, Michael Knopp Biosciences LLC
New Glycinergic Modulators as Potent Painkillers without Negative Psychoactive Effects Pain Xu, Yan Xu, Yan University of Pittsburgh
Non-Addictive Angiotensin AT2 Inhibitors for Neuropathic Pain Relief Neuropathic Pain Katritch, Vsevolod Katritch, Vsevolod University of Southern California
Novel Atypical Dopamine Modulators as Cocaine Pharmacotherapies Novel Atypical Dopamine Modulators as Cocaine Pharmacotherapies Childers, Steven R Childers, Steven R Encepheal Therapeutics, Inc
Optimization of Soluble Gamma-secretase Modulators for the Treatment of Alzheimer Alzheimer's Disease Wagner, Steven Lee Medeiros, Nelson UC San Diego, Massachusetts General Hospital
Orexin Receptor Antagonists for Drug Addiction and Panic Disorder Drug Addiction Kenny, Paul J Kenny, Paul J. Eolas Therapeutics, Inc.
RNA Targeted Drug Discovery and Development for Parkinson’s Disease Parkinson's disease Mouradian, Maral Mouradian, Maral RBHS-Robert Wood Johnson Medical School
Small molecule drugs for treatment of dry age-related macular degeneration Age-Related Macular Degeneration Petrukhin, Konstantin Petrukhin, Konstantin Columbia University
Small molecule mitochondria-targeted therapeutics for AD Alzheimer's Disease Trushina, Eugenia Trushina, Eugenia Mayo Clinic
The Development of Small Molecule Inhibitors for Gaucher Disease Type 3 Gaucher Disease Type 3 Shayman, James Shayman, James University of Michigan
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Form Approved OMB# 0925-0648 Exp. Date 06/2024